The Liver Elastography Machine is a portable, lightweight, and easy-to-carry device designed for non-invasive, accurate, and reliable assessment of liver stiffness and steatosis. It enables patient screening and follow-up anytime, anywhere, making it a versatile tool for healthcare professionals.
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Key Technologies
VCTE™ (Vibration-Controlled Transient Elastography)
* Shear Wave Generation: The probe generates shear waves at a fixed frequency (50Hz), and their propagation speed through the liver is measured via ultrasound to calculate liver stiffness.
* Large Sample Volume: Measures a liver sample volume exceeding 3 cm³ (at least 100 times larger than a biopsy sample).
* Results: Expressed as E (kPa), providing a quantitative measure of liver stiffness.
CAP™ (Controlled Attenuation Parameter)
* Steatosis Quantification: Quantifies liver steatosis by measuring ultrasound attenuation in the liver.
* Validation: CAP values are measured only when the stiffness measurement is valid.
* Probe Compatibility: CAP can be detected using both M+ and XL+ probes.
* Results: Expressed in dB/m, offering a precise measure of liver fat content.
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Product Highlights
* Global Leader in Transient Elastography: Liver Elastography Machine features patented technology clinically validated for non-invasive quantitative assessment of liver stiffness and steatosis.
* Comprehensive Liver Evaluation: Assesses liver fibrosis and steatosis caused by various etiologies, enhancing diagnostic capabilities for liver diseases.
* Evidence-Based: Supported by over 3,500 peer-reviewed publications, ensuring broad clinical applicability.
* Versatile Applications: Suitable for routine examinations in all chronic liver diseases, from general screening to post-liver
transplant follow-up and prognosis assessment.
* Standalone or Adjunct Tool: Can be used independently or alongside liver biopsy to provide precise decision-making support for patient management.
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Clinical Applications
01. Chronic Hepatitis B (HBV)
* Liver Stiffness: Closely correlated with the degree of liver fibrosis in HBV patients.
* CAP Efficacy: High diagnostic accuracy for steatosis, with AUROCs of 0.88 (S>1), 0.92 (S≥2), and 0.94 (S>3).
02. Chronic Hepatitis C (HCV)
* Fibrosis Diagnosis: High accuracy for significant fibrosis, severe fibrosis, and cirrhosis, with AUROCs of 0.79, 0.91, and 0.97, respectively.
* CAP Performance: AUROCs for detecting liver steatosis are 0.8 (S1), 0.86 (S≥2), and 0.88 (S≥3).
03. HCV-HIV Coinfection
* Fibrosis Prediction: Accurately predicts liver fibrosis stages, with AUROCs of 0.80, 0.93, and 0.99 for significant fibrosis,
severe fibrosis, and cirrhosis, respectively.
04. Non-Alcoholic Fatty Liver Disease (NAFLD)
* Steatosis and Fibrosis Assessment: CAP and LSM assess liver steatosis and fibrosis, with AUROCs ranging from 0.70 to 0.89.
05. Alcoholic Liver Disease (ALD)
* Fibrosis Assessment: AUROCs for liver fibrosis are 0.84 (F≤1), 0.91 (F≥2), 0.90 (F≥3), and 0.92 (F=4).
06. Liver Cancer
* Esophageal Varices Prediction: Liver stiffness measurement (LSM) positively correlates with the degree of esophageal varices (EV), with an AUROC of 0.76 for EV prediction.
* Sensitivity: At an LSM of 17.6 kPa, the sensitivity for predicting EV is 90%.
07. Biliary Diseases
* Fibrosis Correlation: Strong correlation with fibrosis in biliary diseases (e.g., primary biliary cholangitis, primary
sclerosing cholangitis).
* Diagnostic Efficacy: AUROCs for diagnosing significant fibrosis, severe fibrosis, or cirrhosis are 0.92, 0.86, 0.95, and 0.96.
08. Autoimmune Liver Disease
* Fibrosis Correlation: Closely correlates with fibrosis in autoimmune hepatitis patients, with an AUROC of 0.95 for cirrhosis diagnosis.
09. Drug-Induced Liver Injury (DILI)
* Fibrosis Diagnosis: Optimal diagnostic performance for fibrosis stages S1, S2, S3, and S4, with AUROCs of 0.81, 0.775, 0.798, and 0.896, respectively.
10. Large-Scale Population Screening
* Cost-Effective: Ideal for screening fatty liver and fibrosis in routine health check-ups.
11. Post-Liver Transplant Follow-Up
* Fibrosis Differentiation: LSM can differentiate between rapid and slow fibrosing patients post-transplant.
* Risk Prediction: A simple score combining bilirubin, LSM, or donor age and 6-month LSM accurately predicts significant fibrosis or portal hypertension risk in HCV patients post-transplant.
12. Metabolic-Associated Fatty Liver Disease (MAFLD)
* Steatosis Detection: CAP is more sensitive than ultrasound in detecting steatosis.
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Advantages of Liver Elastography Machine
* User-Friendly Design: Easy to operate with standardized procedures.
* Immediate Results: High reproducibility and quick turnaround time.
* Dual Metrics: Combines VCTE™ and CAP™ for comprehensive liver assessment.
* Portable: Built-in battery operates for over 2 hours, ideal for on-the-go use.
* Clinically Validated: Supported by extensive research and peer-reviewed publications.
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Clinical Value
* Accurate and Reliable: Reduces the need for invasive procedures like liver biopsy.
* Wide Applicability: Suitable for screening, diagnosis, treatment monitoring, and prognosis assessment.
* Efficient and Convenient: Portable design ideal for large-scale screening and primary healthcare settings.
* Evidence-Based: Extensive clinical research validates its effectiveness, offering scientific support for clinical decision-making.
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Why Choose Liver Elastography Machine?
Liver Elastography Machine is a trusted, non-invasive solution for liver health assessment, offering unparalleled accuracy, ease of use, and clinical versatility. Whether for routine screening or specialized diagnostics, Liver Elastography Machine empowers healthcare providers to deliver better patient outcomes.
Order now to enhance your diagnostic capabilities with Liver Elastography Machine!
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